Immune cells communicate with each other via chemical messages. A chemical, called a cytokine, might direct cells to where they are needed to combat an infection. Yet other cytokines may cause cells to clone themselves to build up an arsenal to fight a specific infection.
Cytokine molecules (also called interleukins, interferons, growth factors and tumor necrosing factors–TNFs) are involved in essentially every important molecular process:
Good and Bad Cytokines
There are both good and bad cytokines. For example, the symptoms of osteoarthritis are likely caused by bad cytokines.
These bad cytokines cause pain, swelling and typically cell death, called a catabolic state. This means tissue is breaking down, causing destruction of the cells and eventually failure of the system.
Good cytokines can be manipulated with both stem cell and PRP injections to counteract bad cytokines. The joint or tendon is transformed into an anabolic state, which means tissue is being built up.
In addition to modulating inflammation, good cytokines help repair tissue, including connective tissue and promote collagen synthesis. They can also direct other cells to areas needing repair and stimulate angiogenesis (meaning it forms blood vessels).
Inflammatory Disease Treatment
Cytokine therapies have tremendous potential for treating and reducing the debilitating effects of a variety of diseases, including some forms of cancer, as well as chronic inflammatory diseases, such as rheumatoid arthritis (RA).
These intercellular communicators help activate numerous processes in the body in virtually all cell types, and they are well known for their role recruiting and activating immune cells in response to injury and infection.
Cytokines are signaling proteins that are produced by white blood cells. They help mediate and regulate immune responses, inflammation and hematopoiesis, which is new blood cell formation. Cytokines form the building blocks of life and are key components in cellular communication.
Cytokines may be classified as peptides, proteins or glycoproteins. From the Greek cyto (“cell”) and kinos (“movement”), cytokines organize cellular tasks. They work as a communication network between cells and immune system cells, among other functions. Cytokines have both direct and indirect effects on stem cells and other types of more mature cells.
Cytokines dramatically affect the micro-environments of the cells by organizing the cellular tasks. By giving the “repair orders” at the cellular level, this causes a cascade of metabolic pathways that extend from the cellular levels to the tissues. Various combinations of cytokines determine what type of repair is needed and then signals the metabolism to download the program of biochemicals to rebuild the connective tissue
Chronic Disease Treatment
Cytokines act as key communicators for immune cells. Maintaining a delicate balance within the multi-levels of these communicators is vital for health.
However, in many chronic diseases, this balance is disrupted. Thus, therapeutic targeting of cytokine pathways promises great hope for patients suffering from chronic diseases.
Tissue Matrix Regeneration
No two patients are alike and utilizing cytokine therapy allows us to control some variables that have limited the body’s capacity to self heal.
MJA Healthcare has made leading-edge cytokine therapies available with FDA-registered oral cytokines. Researcher and expert in cytokine therapy, Dr. A. Artamonov, has developed numerous protocols that can provide extended care and rebuilding of the connective tissue matrix and musculoskeletal components.
Explore MJA Healthcare Network studies and articles as you prepare for your first visit.
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