Regenerative Medicine

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Pure Platelet Rich Plasma Treatments

Bio-Facial Skin Rejuvenation

Platelet Rich Plasma has been used for facial rejuvenation for over 20 years. The procedure has now been perfected with no red blood cells, eliminating the red appearance with Pure PRP. This treatment is ideal for individuals wanting to naturally improve their skin texture, tone and color with no recovery time. The growth factors in Pure PRP stimulate proliferation of fibroblasts and keratinocytes, which aid the body in the production of collagen and keratin. These growth factors also have a significant role in the formation of new blood vessels, synthesizing collagen and hyaluronic acid.

Dr. Mik helps to restore areas of the face that require volume by injecting the Pure PRP into problem areas. The remaining Pure PRP will be painted on the patients face and a derma-roller would then be applied onto the surface of the skin to catalyze facial restoration.

What happens during a facial rejuvenation treatment with PRP?
Dr. Mik will assess the degree of skin aging, perform a simple skin analysis, and recommend injection sites on the face that need to be filled with Pure PRP. The patient’s skin will be cleaned and prepared for a local anesthetic cream to be applied, while nerve blocks may also be given to sensitive areas. Blood will then be drawn from the patient and go through the process of centrifugation. PRP is then injected through a syringe while targeting specific problems. The remaining PRP will subsequently be painted onto the skin and rubbed in with a derma roller.

Is the procedure painful?
In order for the treatment to be comfortable for the patient, their skin has a local anesthetic cream applied 30 minutes before the bio-facial and nerve blocks will be administered to more sensitive areas of concern.

How long is the recovery time?
There is not any downtime for the patient for this procedure. Aesthetically, there may be some redness of the treated areas of the skin and minor bruising for a couple days after the procedure.

How long is the treatment?
The office visit usually takes between 90-120 minutes, while the procedure will only take about 20-30 minutes to complete.

Is it safe?
PRP treatment is extremely safe. Because PRP is produced from your own blood, there is no risk of an allergic reaction. In addition, PRP contains a concentrated amount of white blood cells, your body’s natural defenders against infections. As a result, infection is extremely rare with our PRP treatment.

How many treatments are needed?
Initially, 3 to 6 treatments 4-6 weeks apart are recommended for optimal results. Thereafter, maintenance treatments are recommended every one to two years depending on skin type.

Cytokine Therapy Treatment

Immune cells communicate with each other via chemical messages. A chemical, called a cytokine, might direct cells to where they are needed to combat an infection. Yet other cytokines may cause cells to clone themselves to build up an arsenal to fight a specific infection.

Cytokine molecules (also called interleukins, interferons, growth factors and tumor necrosing factors–TNFs) are involved in essentially every important biological process, from cell proliferation to inflammation, immunity, migration, fibrosis, repair and angiogenesis.

Cytokine Treatment for Debilitating Diseases
Cytokine therapies have tremendous potential for treating and reducing the debilitating effects of a variety of diseases, including some forms of cancer, as well as chronic inflammatory diseases, such as rheumatoid arthritis (RA). These intercellular communicators help activate numerous processes in the body in virtually all cell types, and they are well known for their role recruiting and activating immune cells in response to injury and infection.

Cytokines are signaling proteins that are produced by white blood cells. They help mediate and regulate immune responses, inflammation and hematopoiesis, which is new blood cell formation. Cytokines form the building blocks of life and are key components in cellular communication.

Cytokines may be classified as peptides, proteins or glycoproteins. From the Greek cyto (“cell”) and kinos (“movement”), cytokines organize cellular tasks. They work as a communication network between cells and immune system cells, among other functions. Cytokines have both direct and indirect effects on stem cells and other types of more mature cells.

Cytokines dramatically affect the micro-environments of the cells by organizing the cellular tasks. By giving the “repair orders” at the cellular level, this causes a cascade of metabolic pathways that extend from the cellular levels to the tissues. Various combinations of cytokines determine what type of repair is needed and then signals the metabolism to download the program of biochemicals to rebuild the connective tissue.

Good and Bad Cytokines
There are both good and bad cytokines. For example, the symptoms of osteoarthritis are likely caused by bad cytokines. These bad cytokines cause pain, swelling and typically cell death, called a catabolic state. This means tissue is breaking down, causing destruction of the cells and eventually failure of the system.

Good cytokines can be manipulated with both stem cell and PRP injections to counteract bad cytokines. The joint or tendon is transformed into an anabolic state, which means tissue is being built up.

In addition to modulating inflammation, good cytokines help repair tissue, including connective tissue and promote collagen synthesis. They can also direct other cells to areas needing repair and stimulate angiogenesis (meaning it forms blood vessels).

Cytokine are Key Communicators for Immune Cells
Cytokines act as key communicators for immune cells. Maintaining a delicate balance within the multi-levels of these communicators is vital for health. However, in many chronic diseases, this balance is disrupted. Thus, therapeutic targeting of cytokine pathways promises great hope for patients suffering from chronic diseases.

Leading Edge Oral Cytokines
Guna Biotechnology has made leading-edge cytokine therapies available with FDA-registered oral cytokines. Researcher and expert in cytokine therapy, Dr. Jo Serrentino, has developed numerous protocols that can provide extended care and rebuilding of the connective tissue matrix and musculoskeletal components. No two patients are alike and utilizing cytokine therapy allows us to control some variables that have limited the body’s capacity to self heal.

Stem Cell Rejuvenation

Orthobiologic Stem Cell Therapy

Platelet Rich Plasma Therapy is a new, non-operative treatment that frequently relieves pain and promotes lasting healing of musculoskeletal conditions. PRP Therapy uses components of a person’s own blood cells to formulate a customized concoction that stimulates the natural healing process in many orthopedic conditions. Stem cells, extracted from bone marrow or body fat, may also be used in conjunction with PRP therapy to catalyze the effect. A “fat graft” (adipose sample procured from a mini liposuction) is an excellent source of stem cells, which, when blended with the PRP to stimulate the stem cells to maturation, can often reverse osteoarthritis. The stem cells live much longer than the platelets and therefore may be “boosted” after about a month, increasing the effect of stem cell grafting without having to harvest them again.

The goal of PRP Therapy with stem cells is to resolve pain through real healing. Initial improvement may be seen within a few weeks, gradually increasing as healing progresses. Studies have shown PRP therapy to be frequently effective at relieving pain and returning patients to their normal activities. Both ultrasound and MRI images have shown definitive tissue repair after PRP therapy, confirming the healing process. The need for surgery may be reduced by treating injured tissue before the damage progresses and the condition is irreversible.